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Bricks,Guilherme; Senise,Jorge Figueiredo; Pott-Jr,Henrique; Grandi,Giuliano; Carnaúba-Jr,Dimas; Moraes,Hamilton Antonio Bonilha de; Granato,Celso Franscisco Hernandes; Castelo,Adauto. |
ABSTRACT Background: Hepatitis E virus (HEV) infection in patients with pre-existing liver disease has shown high morbidity and lethality. The consequences of HEV superinfection in patients with chronic hepatitis C virus (HCV) infection are not fully understood. This study aimed to evaluate the association between the presence of anti-HEV antibodies, liver cirrhosis, and insulin resistance. Methods: A total of 618 patients chronically infected with HCV were included from three reference centers for viral hepatitis in São Paulo, Brazil. Presence of anti-HEV IgG was assessed by enzyme-linked immunosorbent assay (WANTAI HEV-IgG ELISA). Results: The seroprevalence of anti-HEV in patients with cirrhosis was significantly higher than in patients without... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis E virus; Hepatitis C virus; Liver cirrhosis; Insulin resistance. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000100045 |
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Bricks,Guilherme; Senise,Jorge Figueiredo; Pott Junior,Henrique; Grandi,Giuliano; Passarini,Amanda; Caldeira,Débora Bellini; Carnaúba Junior,Dimas; Moraes,Hamilton Antonio Bonilha de; Granato,Celso Franscisco Hernandes; Castelo,Adauto. |
ABSTRACT Background and aims: Hepatitis E virus infection in patients with underlying chronic liver disease is associated with liver decompensation and increased lethality. The seroprevalence of hepatitis E virus in patients with chronic hepatitis C in Brazil is unknown. This study aims to estimate the seroprevalence of hepatitis E virus in patients with chronic hepatitis C and to describe associated risk factors. Methods: A total of 618 patients chronically infected with hepatitis C virus from three reference centers of São Paulo, Brazil were included. Presence of anti-HEV IgG was assessed by enzyme-linked immunosorbent assay (WANTAI HEV-IgG ELISA). Results: Out of the 618 patients tested, 10.2% turned out positive for anti-HEV IgG (95% CI 8.0–12.8%).... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis E virus; Hepatitis C virus; Brazil; Seroprevalence. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000200085 |
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